Tricyclics and SSRIs

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منابع مشابه

Choosing between SSRIs and TCAs.

I n the article " Pharmacologic treatment of depression in late life " Alastair Flint gives a thorough and comprehensive review of the treatment of depression. He mentions that to his knowledge, " only 1 trial has compared an SSRI [selective serotonin reuptake inhibitor] (sertra-line) with a secondary amine TCA [tricyclic antidepressant] (nortripty-line), and both drugs were equally well tolera...

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Familial Trichotillomania Responding to SSRIs

Trichotillomania is term used to denote an irresistible urge to pull one’s own hair. It is classified under ‘Habit and Impulse Disorders’. There are few reports of familial occurrence of trichotillomania but none on response to the same SSRI among family members afflicted with trichotillomania. We present a young girl with trichotillomania, who had a family history in her mother. Both responded...

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Triptans, SSRIs/SNRIs and serotonin syndrome.

Serotonin is a naturally occurring “messenger” protein that is found primarily in the gastrointestinal system, certain blood cells (platelets) and the central nervous system (brain and brain stem). Abnormal activity of this messenger protein has been implicated in both migraine and depression, and medications that modify serotonin can be effective in treating both disorders. Such medications in...

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Pharmacogenetics of SSRIs and Sexual Dysfunction

Sexual dysfunction (SD) is a common and disconcerting side effect of selective serotonin reuptake inhibitors (SSRIs) that often influences a patient’s desire to continue long-term antidepressant treatment. Studies specifically assessing changes in sexual wellbeing over time illustrate that the incidence of sexual side effects from SSRIs ranges from 20% to 70%, depending on the characteristics o...

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Pharmacological interventions for people with depression and chronic physical health problems: systematic review and meta-analyses of safety and efficacy.

BACKGROUND Antidepressant drugs are widely used in the treatment of depression in people with chronic physical health problems. AIMS To examine evidence related to efficacy, tolerability and safety of antidepressants for people with depression and with chronic physical health problems. METHOD Meta-analyses of randomised controlled efficacy trials of antidepressants in depression in chronic ...

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ژورنال

عنوان ژورنال: British Journal of Psychiatry

سال: 1996

ISSN: 0007-1250,1472-1465

DOI: 10.1192/bjp.169.2.250b